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Peripartum cardiomyopathy

Cardiomyopathy - peripartum

 

Peripartum cardiomyopathy is a rare disorder in which a pregnant woman's heart becomes weakened and enlarged. It develops during the last month of pregnancy, or within 5 months after the baby is born.

Causes

 

Cardiomyopathy occurs when there is damage to the heart. As a result, the heart muscle becomes weak and does not pump well. This affects the lungs, liver, and other body systems.

Peripartum cardiomyopathy is a form of dilated cardiomyopathy in which no other cause of heart weakening can be found.

It may occur in childbearing women of any age, but it is most common after age 30.

Risk factors for the condition include:

  • Obesity
  • Personal history of cardiac disorders such as myocarditis
  • Use of certain medications
  • Smoking
  • Alcoholism
  • Multiple pregnancies
  • African-American descent
  • Poor nourishment

 

Symptoms

 

  • Fatigue
  • Feeling of heart racing or skipping beats (palpitations)
  • Increased nighttime urination (nocturia)
  • Shortness of breath with activity and when lying flat
  • Swelling of the ankles

 

Exams and Tests

 

During a physical exam, the health care provider will look for signs of fluid in the lungs by touching and tapping with the fingers. A stethoscope will be used to listen for lung crackles, a rapid heart rate, or abnormal heart sounds.

The liver may be enlarged and neck veins may be swollen. Blood pressure may be low or may drop when standing up.

Heart enlargement, congestion of the lungs or the veins in the lungs, decreased cardiac output, decreased movement or functioning of the heart, or heart failure may show up on:

  • Chest x-ray
  • Chest CT scan
  • Coronary angiography
  • Echocardiogram
  • Nuclear heart scan
  • Cardiac MRI

A heart biopsy may help determine if the underlying cause of cardiomyopathy is a heart muscle infection (myocarditis). However, this procedure is not done very often.

 

Treatment

 

A woman may need to stay in the hospital until acute symptoms subside.

Because it is very often possible to restore heart function, and the women who have this condition are often young, everything possible is done to treat the problem.

This may include extreme steps such as:

  • Use of a balloon heart pump (aortic counterpulsation balloon)
  • Immunosuppressive therapy (such as medicines used to treat cancer or prevent rejection of a transplanted organ)
  • Heart transplant if severe congestive heart failure persists

For most women, however, treatment mainly focuses on relieving the symptoms. Some symptoms go away on their own without treatment.

Medicines that are often used include:

  • Digitalis to strengthen the heart's pumping ability
  • Diuretics ("water pills") to remove excess fluid
  • Low-dose beta-blockers

A low-salt diet may be recommended. Fluid may be restricted in some cases. Activities, including nursing the baby, may be limited when symptoms develop.

Daily weighing may be recommended. A weight gain of 3 - 4 pounds or more over 1 or 2 days may be a sign of fluid buildup.

Women who smoke and drink alcohol will be advised to stop, since these habits may make the symptoms worse.

 

Outlook (Prognosis)

 

There are several possible outcomes in peripartum cardiomyopathy. Some women remain stable for long periods, while others get worse slowly.

Others get worse very quickly and may be candidates for a heart transplant. The death rate may be as high as 25 - 50%.

The outlook is good for women whose hearts returns to normal size after the baby is born. If the heart remains enlarged, future pregnancies may result in heart failure. It is not known how to predict who will recover and who will develop severe heart failure.

Women who develop peripartum cardiomyopathy are at high risk of developing the same problem with future pregnancies. They should discuss birth control methods with their health care provider.

 

Possible Complications

 

  • Cardiac arrhythmias (can be deadly)
  • Congestive heart failure
  • Pulmonary emboli (blood clots in the lungs)

 

When to Contact a Medical Professional

 

Call your health care provider if you are currently pregnant or have recently delivered a baby and think you may have signs of cardiomyopathy.

Get medical help right away if you develop chest pain, palpitations, faintness, or other new or unexplained symptoms.

 

Prevention

 

Eat a well-balanced diet and get regular exercise to help keep your heart strong. Avoid cigarettes and alcohol. Your doctor may advise you to avoid getting pregnant again if you have had heart failure during a previous pregnancy.

 

 

References

McKenna W. Diseases of the myocardium and endocardium. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 60.

Warnes CA. Pregnancy and heart disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 82.

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  • Peripartum cardiomyopathy

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    A Closer Look

     

      Tests for Peripartum cardiomyopathy

       
         

        Review Date: 5/13/2014

        Reviewed By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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