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Two different studies. Two different ideas. Both taking the PSA debate head
on.
“PSA was first used clinically in 1988 and was originally developed for following
prostate cancer,” explains Dr. Barry Blitz, a urologist on the medical staff of
Lee Memorial Health System. The first study reports PSA screening decreased prostate
cancer deaths by 20%. The other study found higher levels of PSA screening did not
influence the mortality rate.
The argument: whether or not these numbers could signal a wrong diagnosis. Dr. Blitz
says the focus shouldn’t solely be on the PSA measurement. “In addition, some patients
with some very aggressive prostate cancers may not make any PSA at all. Its not
unusual to do a rectal exam, find a lump in a patient who has essentially a normal
PSA, do a biopsy, and still find prostate cancer.”
He believes it’s too early to dismiss the PSA test all together. “As a screening
test it’s helpful. But by no means is it perfect. In fact, some patients with a
high PSA may not have cancer at all. Sometimes they have a large prostate, he may
have a urinary tract infection, or maybe their prostate cancer just manufactures
a lot of PSA,” explains Dr Blitz.
As the debate over PSAs continues, doctors say until something concrete comes along,
they’ll keep on testing the old-fashioned way.
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